Enterovirus usually is named, digital sequence represents its order. Sequentially, the virus was named the enterovirus type 71 (Human enterovirus 71). Hereinafter referred to as EV71.
Enterovirus 71 (English named: the Human enterovirus 71), referred to as "EV71, is caused by an infant, foot and mouth disease (hand - foot and expressions using diseases; HFMD) one of the main pathogens. Human enterovirus type 71 for the first time in 1969 from California has the central nervous system disease of infants separated from the stool specimens, the virus can be develop in a rhesus monkey kidney cells (rhesus monkey kidney cells; RhMK) and one embryo diploid cells (human fetal diploid cell). If the specimens taken from the patient excrement and organization in human embryonic kidney diploid cells (diploid strain of human fetal kidney cell; HFDK) training; If the throat swab specimens choose human embryo lung diploid cell cells (diploid strain of human fetal lung cell). Through these pure strains of the virus after cell culture analysis, find that there will be a typical caused by enteroviruses cell lesions (cytopathetic effect; CPE) phenomenon, by the electron microscope to observe the shape (morphology) and the physical and chemical, physicochemical properties are similar to the other enteroviruses were known, but in neutralizing antibody test (neutralization test) or immune diffusion test (immunodiffusion test), only to find that it does not have the phenomenon of interaction between, so that the virus was discovered as a new type of intestinal virus, so will the disease strains named enterovirus type 71.
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