Tuesday, April 7, 2015

Loganoside Description



CAS Number:      18524-94-2
Purity:    98%
Molecular Weight:     390.38
Molecular Formula:    C17H26O10
Solubility:      Soluble in water, and 100% ethanol (sparingly). Insoluble in ether, ethyl acetate, and acetone.
Storage:   Store at -20° C
Melting Point:   222-223 °C
Boiling Point:   ~608.77 °C at 760 mmHg (Predicted)
Density:   ~1.50 g/cm3 (Predicted)
Application:     An iridoid glucoside that inhibits Cox-1 and TNF-α formation
Description:
Loganin, an iridoid glucoside, has been appear to be an inhibitor of Cox-1 and aswell acclaimed to abolish TNF-α formation. This admixture aswell has displayed almighty free-radical-scavenging action and inhibitory furnishings on melanogenesis. Research has apparent that Loganin aswell down-regulates mRNA announcement of caspase-3, caspase-9, receptor activator for nuclear agency κ B ligand (RANKL) and up-regulates bcl-2 expression. Experimental studies advance that Loganin can access capacity of osteocalcin and collagen blazon I and aswell advance action of acrid phosphatase.
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