CAS
NO.: 4390-14-5
Molecular
weight: 512.9
Molecular
formula: C22H24N2O8·HCL·1/2C2H5OH·1/2H2O
Other
name: Doxycycline Hydrochloride,Doxycycline,Doxitard,Gibidox,Liomycin
Appearance:
Yellow crystalline powder
Melting
point:206-209?C (dec.)
Solubility
H2O: soluble50mg/mL
Purity:88.0%～94.0%
Application:
API for Antibacterial
Doxycycline hyclate is a constructed tetracycline acquired with agnate antimicrobial
activity.Doxycycline hyclate inhibits the anarchic acknowledgment to the Lyme
Disease Spirochete Borrelia burgdorferi. It is a ample spectrum inhibitor of
cast metalloproteinases in vivo.
Doxycycline
Hyclate is the hyclate alkali anatomy of doxycycline, a synthetic,
broad-spectrum tetracycline antibacterial announcement antimicrobial activity.
Doxycycline hyclate binds reversibly to the 30S ribosomal subunit, possibly to
the 50S ribosomal subunit as well, thereby blocking the bounden of
aminoacyl-tRNA to the mRNA-ribosome complex. This leads to an inhibition of
protein synthesis. In addition, this abettor has apparent inhibition of
collagenase activity.
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