The latanoprost propyl ester prostaglandin F2a, a atypical phenyl another F2a receptor careful agonists. It is a non-active but can rapidly access to the actuality of the cornea, the cornea and the claret can be anatomize to accept the action of the chargeless acid. Can access the address of aqueous amusement through the bend of the eye colorant layer, a baby bulk of drugs, but to advance the aqueous amusement allegation a large, aqueous can access into the eyeball eyelashes choroidal upper, with acceptable IOP blurred effect.
Latanoprost is anatomize in the cornea to the chargeless acerbic from the cornea, this chargeless acerbic to broadcast out of and into the room, to about 2h can ability the aiguille of the blood. 3 ~ 4h IOP began to decline, 8 ~ 12h best decline, advance 24h IOP is not elevated. The biologic aqueous address is discharged, and the half-life of about 2h. Systemic assimilation through the conjunctiva or close membranes, the biologic is captivated in the claret circulatory system, alarmist metabolism mainly with urine excretion.
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