Adverse
furnishings of aldosterone action in the affection and brain, due to changes in
baptize assimilation and elimination of sodium and potassium. Common adverse
biologic reactions (ADRs) associated with the use of eplerenone include:
hyperkalaemia, hypotension, dizziness, adapted renal function, and added
creatinine concentration.
Eplerenone
may accept a lower accident than spironolactone of animal ancillary furnishings
such as feminization, gynecomastia, impotence, low sex drive and abridgement of
admeasurement of macho genitalia. This is because added antimineralocorticoids
accept structural elements of the progesterone molecule, causing progestogenic
and antiandrogenic outcomes.When because demography these medicines, it is
important to agenda the variations in their adeptness to account the nongenomic
furnishings of aldosterone.
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