What is Gabapentin enacarbil?

CAS No.: 222030-63-9

Molecular Formula: C16H27NO6

Molecular Weight: 329.38868

Gabapentin enacarbil is a white to fair apparent solid with a melting access of about 64°C and a solubility of 0.5 mg/mL in water and 10.2 mg/mL in phosphate absorber (pH 6.3).

Gabapentin enacarbil is an anticonvulsant and analgesic biologic of the gabapentinoid class, and a prodrug to gabapentin. It was advised for added articulate bioavailability over gabapentin, and beastly trials showed it to aftermath continued absolution of gabapentin with about alert the all-embracing bioavailability, abnormally if taken with a fatty meal.Gabapentin enacarbil has anesthetized beastly analytic trials for the analysis of active legs syndrome, and antecedent after-effects accept apparent it to be able-bodied acceptable and analytic effective.

Gabapentin enacarbil was denied approval by the U.S. Food and Biologic Administration (FDA) in February 2010, citation apropos about accessible added blight accident apparent by some beastly studies. Similar apropos had been aloft about gabapentin itself in the past, but were acquainted to be outweighed by its analytic account as an anticonvulsant, admitting the analysis of active legs affection was not apparent to absolve the aforementioned affectionate of risk.