Tasimelteon Description

Tasimelteon is a careful bifold melatonin receptor agonist adumbrated for the analysis of Non-24-Hour Sleep-Wake Disorder (N24HSWD). Occurring frequently in dark individuals after ablaze perception, this action is generally characterized by periods of night-time indisposition and day-time sleepiness. In dark individuals, a abridgement of ablaze dispatch causes an addendum of the 24-hour circadian aeon and can advance to progressively delayed beddy-bye onset. By activating melatonin receptors MT1 and MT2 in the suprachiasmatic root of the brain, tasimelteon has been apparent to advance beddy-bye by resynchronizing the circadian accent through its "non-photic" mechanism. Tasimelteon is currently the alone biologic accessible for the analysis of N24HSWD and was accepted drop biologic cachet by the FDA in 2010.

Tasimelteon is a careful bifold agonist of the melatonin receptors MT1 and MT2.